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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
9.09
Human Site:
T389
Identified Species:
18.18
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.55
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
T389
N
L
E
N
I
I
D
T
Y
S
A
R
T
I
Q
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
T391
N
L
E
N
I
I
D
T
Y
S
A
R
T
I
Q
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
K361
K
L
K
P
I
L
T
K
Y
S
A
R
D
L
Q
Dog
Lupus familis
XP_546737
807
92419
V417
N
L
E
E
I
I
D
V
Y
S
A
R
T
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
S375
N
L
E
D
I
I
D
S
Y
S
A
R
T
M
Q
Rat
Rattus norvegicus
P0C1T0
774
89178
V384
N
L
E
E
I
I
D
V
F
P
A
Q
T
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
K359
E
L
K
A
I
I
S
K
Y
S
A
S
T
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
K365
K
L
S
E
V
L
S
K
H
S
H
R
T
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
H462
E
M
G
K
I
L
A
H
T
D
R
R
V
V
H
Honey Bee
Apis mellifera
XP_392502
776
89056
R389
Q
M
G
R
I
V
K
R
T
D
R
R
T
L
H
Nematode Worm
Caenorhab. elegans
O16796
848
97043
K459
H
V
S
E
L
I
E
K
T
D
V
G
L
L
T
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
R377
D
V
L
A
L
V
Q
R
T
P
L
R
I
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
46.6
80
N.A.
80
60
N.A.
N.A.
60
N.A.
33.3
N.A.
13.3
20
6.6
6.6
P-Site Similarity:
100
100
66.6
86.6
N.A.
100
80
N.A.
N.A.
66.6
N.A.
60
N.A.
33.3
40
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
9
0
0
0
59
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
42
0
0
25
0
0
9
0
0
% D
% Glu:
17
0
42
34
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
9
9
0
9
0
0
0
17
% H
% Ile:
0
0
0
0
75
59
0
0
0
0
0
0
9
25
0
% I
% Lys:
17
0
17
9
0
0
9
34
0
0
0
0
0
0
0
% K
% Leu:
0
67
9
0
17
25
0
0
0
0
9
0
9
50
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
17
0
% M
% Asn:
42
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
9
0
0
0
0
9
0
0
67
% Q
% Arg:
0
0
0
9
0
0
0
17
0
0
17
75
0
0
0
% R
% Ser:
0
0
17
0
0
0
17
9
0
59
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
17
34
0
0
0
67
0
9
% T
% Val:
0
17
0
0
9
17
0
17
0
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _